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A description of the capabilities and limitations of biochemistry-based methods for analyzing the brain.
The anatomies of simple amino acid transmitter systems— such as glutamate, aspartate, glycine, and GABA—have been quite difficult to study not only because they are widespread in the brain but also because most of the molecules participate in various aspects of general cellular metabolism. Since these transmitters appea....
Panksepp, Jaak, "Affective Neuroscience: The Foundations of Human and Animal Emotions", Oxford University Press, 1998, 113
For instance, at present over a dozen receptors are known to receive messages from the transmitter serotonin, and identification of the functions of each subtype is an active area of inquiry because serotonin figures in virtually all psychiatric disorders. In addition, the brain contains receptors for many peripheral ho....
Panksepp, Jaak, "Affective Neuroscience: The Foundations of Human and Animal Emotions", Oxford University Press, 1998, 100
[Peptides are small chains of amino acids. Many of these are brain neurotransmitters. They are] the most promising candidates for mediating specific behavioral and psychological functions. [They are hard to manipulate within the living brain. Most are broken down in digestion, and most can't cross the BBB, although some....
Panksepp, Jaak, "Affective Neuroscience: The Foundations of Human and Animal Emotions", Oxford University Press, 1998, 106
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