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This page is incomplete. It displays memoes and/or notes.
Makeup and behavior of the CNS at the cellular level. Also, the cerebrospinal fluid and movement of active chemicals via circulation and diffusion.
Humoral mediators secreted by resident or infiltrating pro-nociceptive helper cells may diffuse through the spinal parenchyma [the tissue of the spine] and modify nociception.
In the CNS three types of glial cells can be distinguished: microglia, astrocytes, and oligodendrocytes. The role, if any, of the latter for....
McMahon, S. B., Koltzenberg, M., Tracy, I., and Turk, D. C., "Wall and Melzack's Textbook of Pain", Elsevier Saunders, 2013, 103-4
This phenotypic diversity includes proliferative, migrational, and phagocytic responses associated with a canon of expression of pro- and anti-inflammatory molecules. These responses are in addition to the immune role of microglia in antigen presentation and T-cell recruitment.
McMahon, S. B., Koltzenberg, M., Tracy, I., and Turk, D. C., "Wall and Melzack's Textbook of Pain", Elsevier Saunders, 2013, 74-75
Considerable evidence has identified the mitogen-activated protein kinases (MAPKs) as a candidate family of intracellular mediators. Of the MAPKs, p38 appears to be heavily implicated in microglia-mediated, post-nerve injury pain states and has been identified as the intracellular mediator of P2X4R-brain-derived neurot....
McMahon, S. B., Koltzenberg, M., Tracy, I., and Turk, D. C., "Wall and Melzack's Textbook of Pain", Elsevier Saunders, 2013, 73
End of included memoes/notes
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The Blood-Brain Barrier (This page is incomplete.)
Astrocytes and Microglia (Last updated: Wed, Jun 21, 2017)
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Injury, Inflammation, and Healing (This page is incomplete.)