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Phineas Gage and Brain Modularity


This page is incomplete. It displays memoes and/or notes.

Meta description

The case of Phineas Gage revealed the modular nature of the brain. The behaviorist view of psychology is being superceded by a neurophysiological view based on advances in neuroscience since the 1990s. This change of views affects understandings of pain.

Title Memo

The modularity of the brain is illustrated by the Phineas Gage episode. The triune brain model. Brain stem, limbic system, neocortex. The roles of each. "Mood" or "phase-controlling" neurotransmitter systems centered in the limbic system, NE, DA, etc. Emotion as understood in affective neuroscience. The general structure of the basic emotional systems, connections up and down the brain. Evidence for their existence and examples of behavior.

Note Text: 1603 Phineas Gage

[Phineas Gage was a railroad worker in 1848, polite, hardworking, pleasant and responsible, until the explosive charge which he’d been tamping exploded prematurely. His tamping iron penetrated his cheek and emerged from the other side of his skull. Rather than dying, he soon recovered consciousness and went on to lead a....

Damasio, Antonio R., "Descartes' Error: Emotion, Reason, and the Human Brain", Penguin Books, 1994, 10

Note Text: 1604 Phineas Gage examplar of brain's modularity

Gage’s example indicated that something in the brain was concerned specifically with unique human properties, among them the ability to anticipate the future and plan accordingly within a complex social environment; the sense of responsibility toward the self and others; and the ability to orchestrate one’s survival....

Damasio, Antonio R., "Descartes' Error: Emotion, Reason, and the Human Brain", Penguin Books, 1994, 10

Note Text: 1605 Modules degenerated with others intact

Another important aspect of Gage’s story is the discrepancy between the degenerated character and the apparent intactness of the several instruments of mind—attention, perception, memory, language, intelligence.

Damasio, Antonio R., "Descartes' Error: Emotion, Reason, and the Human Brain", Penguin Books, 1994, 11

Note Text: 1242 Conceptual shift in psychology, etc.

The study of brains and behaviors finds itself in the middle of a conceptual shift. Historically, clinicians and lawyers have agreed on an intuitive distinction between neurological disorders ("brain problems") and psychiatric disorders ("mind problems"). As recently as a century ago, the prevailing attitude was to get....

Pinker, Steven, "The Blank Slate: The Modern Denial of Human Nature", Viking, 2002, 172

Note Text: 1606 Scientific camps over modularity of brain

…two camps were beginning to form. One held that psychological functions such as language or memory could never be traced to a particular region of the brain. If one had to accept, reluctantly, that the brain did produce the mind, it did so as a whole and not as a collection of parts with special functions. The other ca....

Damasio, Antonio R., "Descartes' Error: Emotion, Reason, and the Human Brain", Penguin Books, 1994, 12

Note Text: 1607 Biological modules could be separate

[At the time of the Gage incident,] It was acceptable that the brain sectors whose damage would have caused Gage’s heart to stop pumping and his lungs to stop breathing had not been touched by the iron rod. It was also acceptable that the brain sectors which control wakefulness were far from the iron’s course and were t....

Damasio, Antonio R., "Descartes' Error: Emotion, Reason, and the Human Brain", Penguin Books, 1994, 12-13

Note Text: 1638 Key brain subsystems are genetically preserved

[The structure of key brain subsystems, however, is determined genetically. This likely applies to the brain stem, hypothalamus, and basal forebrain, and the amygdala and cingulate cortex, which are highly preserved among mammalian species.]

Damasio, Antonio R., "Descartes' Error: Emotion, Reason, and the Human Brain", Penguin Books, 1994, 109-10

Note Text: 1639 Roles of cortex and basic structures

[Those innate, genetically organized structures shape the development of the more-modern cortex that provides the ability to visualize and reason.] … (1) the innate regulatory circuits are involved in the business of organism survival and because of that they are privy to what is happening in the more modern sectors of....

Damasio, Antonio R., "Descartes' Error: Emotion, Reason, and the Human Brain", Penguin Books, 1994, 111

End of included memoes/notes