Spinal Inhibition and Excitation

Last updated: Tue, Nov 19, 2024

The spine contains mechanisms that raise and lower its level of excitation even if it is separated from the brain. When nociceptive spinal circuits are more excited, they can transmit more nociceptive signals to the brain.

Reducing the firing rate of spinal neurons reduces pain because the nervous system "decides" what is painful not only by which receptors are activated, but also by the frequency of signals in these spinal neurons.


Within this section...

Ascending Nociceptive Circuits (Last updated: Tue, Nov 19, 2024)

Descending Nociceptive Circuits (Last updated: Fri, Jul 26, 2024)

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Pain Phenomena of the Spine and Periphery (Last updated: Wed, Jul 5, 2017)