Note Text: 1133 Evolution of pathological pain syndromes

Neither diseases nor the pain mechanisms that accompany them are stationary processes. Rather, dynamic, continuous changes occur in both as time progresses. During the first few seconds after a peripheral injury, the associated pain is obviously triggered by nerve impulses from the periphery. In the minutes, days and we....

Melzack, R. and Wall, P. D., "The Challenge of Pain (Reprint of 1988 edition)", Penguin Books, 2008, 77