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...Fatigue is often present in CPPs, especially those with fibromyalgia, in whom the prevalence of substantial fatigue has been reported to be twice that in those with rheumatoid arthritis or osteoarthritis. A structured evidence-based review of 23 reports concluded that there is an association between pain and fatigue....
Fishbain, David A., "Psychiatric Pain-Associated Co-morbidities", Chapter 19 of McMahon et al. 2013, 2013, 278-9
“One piece of evidence for how expensive (and important) the immune system is comes from “sickness behavior”—the cost the immune system imposes on the rest of the body when it needs to repair itself. Right after the immune system has fought off a parasitic invader—let us say a virus or bacteria—it is physiologically exh....
Trivers, Robert, "The Folly of Fools", Basic Books, 2011, 119
“…corticosteroids—produced in response to stress and associated with anxiety and fear—are immune suppressors.” [122] [Segerstrom, S. C., & Miller, G. E. (2004). Psychological stress and the human immune system: a meta-analytic study of 30 years of inquiry. Psychological Bulletin 130(4):601-630.]
Trivers, Robert, "The Folly of Fools", Basic Books, 2011, 122
Rich reported that the group of incest survivors had abnormalities in their CD45 RA-to-RO ratio, compared with their nontraumatized peers. CD45 cells are the "memory cells” of the immune system. Some of them, called RA cells, have been activated by past exposure to toxins; they quickly respond to environmental threats t....
Van Der Kolk, Bessel, "The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma", Penguin Books, 2015, 129
Helplessness and immobilization keep people from utilizing their stress hormones to defend themselves. When that happens, their hormones still are being pumped out, but the actions they’re supposed to fuel are thwarted. Eventually, the activation patterns that were meant to promote coping are turned back against the org....
Van Der Kolk, Bessel, "The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma", Penguin Books, 2015, 219
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