Adaptation to Pain


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Title Memo

Understandings of how our motor system may adapt to pain, e.g., DNS

Note Text: 1488 Mirror box therapy

[Therapy using the mirror box proved most effective for those with more recent disability. Those with longer duration needed more gradual approaches to increased movement, starting with visualization. Doidge’s interpretation is that using the mirror box bypassed the connection between the motor and pain circuits, eventu....

Norman Doidge. M.D., "The Brain That Changes Itself", Penguin Books, 2007, 193-4

Note Text: 1608 Strong emotions can block pain

“Having observed that 75 percent of severely wounded soldiers on the Italian front did not request morphine, a surgeon by the name of Harry K. Beecher speculated that ‘strong emotions can block pain.’…We concluded that Beecher’s speculation that ‘strong emotions can block pain’ was the result of the release of morphinel....

Van Der Kolk, Bessel, "The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma", Penguin Books, 2015, 33

Note Text: 1487 Preemptive pain

“Now suppose, thought Ramachandran, the brain prevents the mistaken movement [expected to cause pain] by triggering pain the moment before the movement takes place, between the time when the motor center issues the command to move and the time when the move is performed. What better way for the brain to prevent movement....

Norman Doidge. M.D., "The Brain That Changes Itself", Penguin Books, 2007, 193

Note Text: 1812 Trauma moves focus away from everyday life

Recent studies of Australian combat veterans show that their brains are rewired to be alert for emergencies, at the expense of being focused on the small details of everyday life.

Van Der Kolk, Bessel, "The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma", Penguin Books, 2015, 223

Note Text: 1819 Memories evolve in deep and REM sleep

Today we know that both deep sleep and REM sleep play important roles in how memories change over time. The sleeping brain reshapes memory by increasing the imprint of emotionally relevant information while helping irrelevant material fade away. In a series of elegant studies Stickgold and his colleagues showed that the....

Van Der Kolk, Bessel, "The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma", Penguin Books, 2015, 262

Note Text: 1821 Helplessness to tension to physical pain

One of the ways the memory of helplessness is stored is as muscle tension or feelings of disintegration in the affected body areas: head, back, and limbs in accident victims, vagina and rectum in victims of sexual abuse. The lives of many trauma survivors come to revolve around bracing against and neutralizing unwanted....

Van Der Kolk, Bessel, "The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma", Penguin Books, 2015, 267-8

Note Text: 1822 Chronic anger or fear

When people are chronically angry or scared, constant muscle tension ultimately leads to spasms, back pain, migraine headaches, fibromyalgia, and other forms of chronic pain. They may visit multiple specialists, undergo extensive diagnostic tests, and be prescribed multiple medications, some of which may provide tempora....

Van Der Kolk, Bessel, "The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma", Penguin Books, 2015, 268

Note Text: 1829 Evidence of negative cognitive effects with trauma

[The two groups were given the task of identifying which item in a picture wasn't like the others.]

In the "normal” group key parts of the brain worked together to produce a coherent pattern of filtering, focus, and analysis. (See left image below. [Charts of EEG readings]) In contrast, the brain waves of traumatiz....

Van Der Kolk, Bessel, "The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma", Penguin Books, 2015, 313

Note Text: 2091 Many affects are related to fear and anxiety

In addition to various forms of anxiety, there are many other types of aversive internal feelings—ranging from pain to hunger, thirst, and other bodily needs--that may modulate the intensity of fear. It is especially important to consider the role of pain in the genesis of anxiety, since that has been the traditional wa....

Panksepp, Jaak, "Affective Neuroscience: The Foundations of Human and Animal Emotions", Oxford University Press, 1998, 215

Note Text: 2087 Many types of learned fears exist

[Behavioral research into fear and anxiety has shown that there are multiple types of learned fears. Neuroscience shows that there are many interrelated neural systems that account for this, although these have not all been teased out.]

Panksepp, Jaak, "Affective Neuroscience: The Foundations of Human and Animal Emotions", Oxford University Press, 1998, 208-12

Note Text: 2070 Sugar releases opioids and causes analgesia

...sweet substances have been found to promote opioid release in the brain, and young animals (as well as human babies) become analgesic and cry less after the administration of sugar water into their mouths. Again, these effects are partly reversed by opiate receptor antagonists.

Panksepp, Jaak, "Affective Neuroscience: The Foundations of Human and Animal Emotions", Oxford University Press, 1998, 184

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